Total Recoverin Cell-Based Colorimetric ELISA Kit
- Catalog No.:KA3591C
- Applications:ELISA
- Reactivity:Human;Mouse
- Gene Name:
- RCVRN
- Human Gene Id:
- 5957
- Human Swiss Prot No:
- P35243
- Mouse Swiss Prot No:
- P34057
- Storage Stability:
- 2-8°C/6 months
- Other Name:
- Recoverin (Cancer-associated retinopathy protein) (Protein CAR)
- Detection Method:
- Colorimetric
- Background:
- disease:Identified as the antigen in cancer-associated retinopathy, an autoimmune disease of the retina caused by a tumor in another tissue.,function:Seems to be implicated in the pathway from retinal rod guanylate cyclase to rhodopsin. May be involved in the inhibition of the phosphorylation of rhodopsin in a calcium-dependent manner. The calcium-bound recoverin prolongs the photoresponse.,miscellaneous:Binds two calcium ions; one with high affinity, the other with low affinity.,similarity:Belongs to the recoverin family.,similarity:Contains 4 EF-hand domains.,tissue specificity:Retina and pineal gland.,
- Function:
- sensory perception, visual perception, phototransduction, response to radiation, response to light stimulus, detection of external stimulus, detection of abiotic stimulus, detection of light stimulus, response to abiotic stimulus, regulation of metal ion transport, regulation of ion transport, neurological system process, cognition, sensory perception of light stimulus, detection of stimulus, regulation of calcium ion transport,
- Subcellular Location:
- Photoreceptor inner segment . Cell projection, cilium, photoreceptor outer segment . Photoreceptor outer segment membrane ; Lipid-anchor ; Cytoplasmic side . Perikaryon . Primarily expressed in the inner segments of light-adapted rod photoreceptors, approximately 10% of which translocates from photoreceptor outer segments upon light stimulation (By similarity). Targeting of myristoylated protein to rod photoreceptor outer segments is calcium dependent (By similarity). .
- Expression:
- Retina and pineal gland.
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