Total TIS11D Cell-Based Colorimetric ELISA Kit
- Catalog No.:KA3614C
- Applications:ELISA
- Reactivity:Human;Mouse
- Gene Name:
- ZFP36L2
- Human Gene Id:
- 678
- Human Swiss Prot No:
- P47974
- Mouse Swiss Prot No:
- P23949
- Storage Stability:
- 2-8°C/6 months
- Other Name:
- Zinc finger protein 36, C3H1 type-like 2 (ZFP36-like 2) (Butyrate response factor 2) (EGF-response factor 2) (ERF-2) (Protein TIS11D)
- Detection Method:
- Colorimetric
- Background:
- function:Probable regulatory protein involved in regulating the response to growth factors. RNA-binding protein that binds to 5'UUAUUUAUUU-3' core sequence. Binds to the class II AU-rich element (ARE) in the 3'-UTR of target mRNAs and promotes their deadenylation and degradation.,similarity:Contains 2 C3H1-type zinc fingers.,
- Function:
- nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA catabolic process, RNA catabolic process, mRNA catabolic process, cell proliferation, macromolecule catabolic process,posttranscriptional regulation of gene expression, mRNA metabolic process, regulation of RNA stability, regulation of mRNA stability, cellular macromolecule catabolic process, regulation of RNA metabolic process,
- Subcellular Location:
- Nucleus . Cytoplasm . Shuttles between the nucleus and the cytoplasm in a XPO1/CRM1-dependent manner. .
- Expression:
- Expressed mainly in the basal epidermal layer, weakly in the suprabasal epidermal layers (PubMed:27182009). Expressed in epidermal keratinocytes (at protein level) (PubMed:27182009).
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