Total Hox-A1 Cell-Based Colorimetric ELISA Kit

  • Catalog No.：KA3616C
  • Applications：ELISA
  • Reactivity：Human;Mouse;Rat
    • Gene Name：
    • HOXA1
    • Human Gene Id：
    • 3198
    • Human Swiss Prot No：
    • P49639
    • Mouse Swiss Prot No：
    • P09022
    • Storage Stability：
    • 2-8°C/6 months
    • Other Name：
    • Homeobox protein Hox-A1 (Homeobox protein Hox-1F)
    • Detection Method：
    • Colorimetric
    • Background：
    • disease:Defects in HOXA1 are the cause of Athabaskan brainstem dysgenesis syndrome (ABSD) [MIM:601536]; also known as Narvajo brainstem syndrome. This syndrome is characterized by horizontal gaze palsy, sensorineural deafness, central hypoventilation, and developmental delay. Some patients had swallowing dysfunction, vocal cord paralysis, facial paresis, seizures, and cardiac outflow tract anomalies.,disease:Defects in HOXA1 are the cause of Bosley-Salih-Alorainy syndrome (BSAS) [MIM:601536]. Affected individuals show horizontal gaze abnormalities, deafness, facial weakness, vascular malformations of the internal carotid arteries and cardiac outflow trac. Some patients manifest mental retardation and autism spectrum disorder. In contrast to individuals with ABSD, central hypoventilation is not observed in individuals with BSAS.,function:Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures. Seems to act in the maintenance and/or generation of hindbrain segments.,similarity:Belongs to the Antp homeobox family. Labial subfamily.,similarity:Contains 1 homeobox DNA-binding domain.,
    • Function：
    • cell morphogenesis, cell morphogenesis involved in differentiation, regionalization, transcription, regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, cell motion, pattern specification process, axonogenesis, axon guidance, sensory organ development, motor axon guidance, positive regulation of biosynthetic process, anterior/posterior pattern formation, positive regulation of macromolecule biosynthetic process, positive regulation of macromolecule metabolic process, positive regulation of gene expression,cranial nerve development, rhombomere development, pons development, facial nerve development, rhombomere 3 development, rhombomere 4 development, rhombomere 5 development, cranial nerve morphogenesis, cranial nerve structural organization, facial nerve morphogenesis, facial nerve structural organization, nerve development, facial nucl
    • Subcellular Location：
    • Nucleus .

    Attributes

    • Code：
    • KA3616C
    • Size
    • 96 / well
    • Price$：
    • 330
    • Delivery：
    • 2024-12-09
    Order

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