Total CLK2 Cell-Based Colorimetric ELISA Kit

  • Catalog No.：KA3619C
  • Applications：ELISA
  • Reactivity：Human;Mouse;Rat
    • Gene Name：
    • CLK2
    • Human Gene Id：
    • 1196
    • Human Swiss Prot No：
    • P49760
    • Mouse Swiss Prot No：
    • O35491
    • Storage Stability：
    • 2-8°C/6 months
    • Other Name：
    • Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)
    • Detection Method：
    • Colorimetric
    • Background：
    • catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates serines, threonines and tyrosines.,PTM:Autophosphorylates on all three types of residues.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. Lammer subfamily.,similarity:Contains 1 protein kinase domain.,
    • Function：
    • protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, phosphorylation,
    • Subcellular Location：
    • Nucleus .; [Isoform 1]: Nucleus . Nucleus speckle . Inhibition of phosphorylation at Ser-142 results in accumulation in the nuclear speckle. .; [Isoform 2]: Nucleus speckle . Co-localizes with serine- and arginine-rich (SR) proteins in the nuclear speckles. .
    • Expression：
    • Endothelial cells (PubMed:19168442). Expressed in androgen-dependent prostate cancer cells (PubMed:28289210).

    Attributes

    • Code：
    • KA3619C
    • Size
    • 96 / well
    • Price$：
    • 330
    • Delivery：
    • 2024-12-09
    Order

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