Total hnRNP M Cell-Based Colorimetric ELISA Kit
- Catalog No.:KA3629C
- Applications:ELISA
- Reactivity:Human;Mouse;Rat
- Gene Name:
- HNRNPM
- Human Gene Id:
- 4670
- Human Swiss Prot No:
- P52272
- Mouse Swiss Prot No:
- Q9D0E1
- Rat Swiss Prot No:
- Q62826
- Storage Stability:
- 2-8°C/6 months
- Other Name:
- Heterogeneous nuclear ribonucleoprotein M (hnRNP M)
- Detection Method:
- Colorimetric
- Background:
- alternative products:Experimental confirmation may be lacking for some isoforms,function:Pre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro. Involved in splicing. Acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines.,PTM:Sumoylated.,similarity:Contains 3 RRM (RNA recognition motif) domains.,subunit:Identified in the spliceosome C complex, at least composed of AQR, ASCC3L1, C19orf29, CDC40, CDC5L, CRNKL1, DDX23, DDX41, DDX48, DDX5, DGCR14, DHX35, DHX38, DHX8, EFTUD2, FRG1, GPATC1, HNRPA1, HNRPA2B1, HNRPA3, HNRPC, HNRPF, HNRPH1, HNRPK, HNRNPM, HNRPR, HNRPU, KIAA1160, KIAA1604, LSM2, LSM3, MAGOH, MORG1, PABPC1, PLRG1, PNN, PPIE, PPIL1, PPIL3, PPWD1, PRPF19, PRPF4B, PRPF6, PRPF8, RALY, RBM22, RBM8A, RBMX, SART1, SF3A1, SF3A2, SF3A3, SF3B1, SF3B2, SF3B3, SFRS1, SKIV2L2, SNRPA1, SNRPB, SNRPB2, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF, SNRPG, SNW1, SRRM1, SRRM2, SYF2, SYNCRIP, TFIP11, THOC4, U2AF1, WDR57, XAB2 and ZCCHC8.,
- Function:
- RNA splicing, via transesterification reactions, RNA splicing, via transesterification reactions with bulged adenosine as nucleophile, nuclear mRNA splicing, via spliceosome, RNA processing, mRNA processing, RNA splicing, mRNA metabolic process,
- Subcellular Location:
- Nucleus, nucleolus .
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