Total ADAR2 Cell-Based Colorimetric ELISA Kit

  • Catalog No.：KA3663C
  • Applications：ELISA
  • Reactivity：Human;Mouse;Rat
    • Gene Name：
    • ADARB1
    • Human Gene Id：
    • 104
    • Human Swiss Prot No：
    • P78563
    • Mouse Swiss Prot No：
    • Q91ZS8
    • Storage Stability：
    • 2-8°C/6 months
    • Other Name：
    • Double-stranded RNA-specific editase 1 (EC 3.5.-.-) (RNA-editing deaminase 1) (RNA-editing enzyme 1) (dsRNA adenosine deaminase)
    • Detection Method：
    • Colorimetric
    • Background：
    • alternative products:Additional isoforms seem to exist,cofactor:Binds 1 inositol hexakisphosphate (IP6) per subunit.,function:Editing of the messenger RNAs for glutamate receptor (GluR) subunits by site-selective adenosine deamination. Edits both the GluR-B Q/R and R/G sites efficiently but converts the adenosine in hotspot1 much less efficiently.,similarity:Contains 1 A to I editase domain.,similarity:Contains 2 DRBM (double-stranded RNA-binding) domains.,
    • Function：
    • RNA processing, mRNA processing, RNA modification, mRNA metabolic process, base conversion or substitution editing,
    • Subcellular Location：
    • Nucleus . Nucleus, nucleolus . Shuttles between nucleoli and the nucleoplasm. .; [Isoform 1]: Nucleus . Nucleus, nucleolus .; [Isoform 2]: Nucleus . Nucleus, nucleolus .
    • Expression：
    • Highly expressed in brain and heart and at lower levels in placenta. Fair expression in lung, liver and kidney. Detected in brain, heart, kidney, lung and liver (at protein level). ; [Isoform 5]: Highly expressed in hippocampus and colon. Expressed in pediatric astrocytomas and the protein has a decreased RNA-editing activity. The decrease in RNA editing correlates with the grade of malignancy of the tumors, with the high grade tumors showing lower editing is seen.

    Attributes

    • Code：
    • KA3663C
    • Size
    • 96 / well
    • Price$：
    • 330
    • Delivery：
    • 2024-12-09
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