Total MKP-2 Cell-Based Colorimetric ELISA Kit
- Catalog No.:KA3702C
- Applications:ELISA
- Reactivity:Human;Mouse;Rat
- Gene Name:
- DUSP4
- Human Gene Id:
- 1846
- Human Swiss Prot No:
- Q13115
- Mouse Swiss Prot No:
- Q8BFV3
- Rat Swiss Prot No:
- Q62767
- Storage Stability:
- 2-8°C/6 months
- Other Name:
- Dual specificity protein phosphatase 4 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity protein phosphatase hVH2) (Mitogen-activated protein kinase phosphatase 2) (MAP kinase phosphatase 2) (MKP-2)
- Detection Method:
- Colorimetric
- Background:
- catalytic activity:A phosphoprotein + H(2)O = a protein + phosphate.,catalytic activity:Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.,function:Regulates mitogenic signal transduction by dephosphorylating both Thr and Tyr residues on MAP kinases ERK1 and ERK2.,similarity:Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.,similarity:Contains 1 rhodanese domain.,similarity:Contains 1 tyrosine-protein phosphatase domain.,
- Function:
- MAPKKK cascade, protein amino acid dephosphorylation, phosphorus metabolic process, phosphate metabolic process,intracellular signaling cascade, protein kinase cascade, response to organic substance, dephosphorylation,
- Subcellular Location:
- Nucleus .
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