Total MELK Cell-Based Colorimetric ELISA Kit
- Catalog No.:KA3734C
- Applications:ELISA
- Reactivity:Human
- Gene Name:
- MELK
- Human Gene Id:
- 9833
- Human Swiss Prot No:
- Q14680
- Mouse Swiss Prot No:
- Q61846
- Storage Stability:
- 2-8°C/6 months
- Other Name:
- Maternal embryonic leucine zipper kinase (hMELK) (EC 2.7.11.1) (Protein kinase Eg3) (pEg3 kinase) (Protein kinase PK38) (hPK38) (Tyrosine-protein kinase MELK) (EC 2.7.10.2)
- Detection Method:
- Colorimetric
- Background:
- catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Phosphorylates ZNF622 and may contribute to its redirection to the nucleus. May be involved in the inhibition of spliceosome assembly during mitosis.,PTM:Autophosphorylated. Thr-478 phosphorylation during mitosis promotes interaction with PPP1R8.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.,similarity:Contains 1 KA1 (kinase-associated) domain.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with ZNF622 and PPP1R8.,tissue specificity:Expressed in placenta, kidney, thymus, testis, ovary and intestine.,
- Function:
- protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, phosphorylation,
- Subcellular Location:
- Cell membrane ; Peripheral membrane protein .
- Expression:
- Expressed in placenta, kidney, thymus, testis, ovary and intestine.
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