Total ERK 3 Cell-Based Colorimetric ELISA Kit
- Catalog No.:KA3769C
- Applications:ELISA
- Reactivity:Human;Mouse;Rat
- Gene Name:
- MAPK6
- Human Gene Id:
- 5597
- Human Swiss Prot No:
- Q16659
- Mouse Swiss Prot No:
- Q61532
- Rat Swiss Prot No:
- P27704
- Storage Stability:
- 2-8°C/6 months
- Other Name:
- Mitogen-activated protein kinase 6 (MAP kinase 6) (MAPK 6) (EC 2.7.11.24) (Extracellular signal-regulated kinase 3) (ERK-3) (MAP kinase isoform p97) (p97-MAPK)
- Detection Method:
- Colorimetric
- Background:
- catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,domain:The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.,enzyme regulation:Activated by threonine and tyrosine phosphorylation.,function:Phosphorylates microtubule-associated protein 2 (MAP2). May promote entry in the cell cycle.,PTM:Dually phosphorylated on Thr-626 and Tyr-628, which activates the enzyme.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.,similarity:Contains 1 protein kinase domain.,tissue specificity:Highest expression in the skeletal muscle, followed by the brain. Also found in heart, placenta, lung, liver, pancreas, kidney and skin fibroblasts.,
- Function:
- protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, cell cycle,phosphorylation,
- Subcellular Location:
- Cytoplasm . Nucleus . Translocates to the cytoplasm following interaction with MAPKAPK5. .
- Expression:
- Highest expression in the skeletal muscle, followed by the brain. Also found in heart, placenta, lung, liver, pancreas, kidney and skin fibroblasts.
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