Total AAK1 Cell-Based Colorimetric ELISA Kit

  • Catalog No.:KA3776C
  • Applications:ELISA
  • Reactivity:Human;Mouse;Rat
    • Gene Name:
    • AAK1
    • Human Swiss Prot No:
    • Q2M2I8
    • Mouse Swiss Prot No:
    • Q3UHJ0
    • Storage Stability:
    • 2-8°C/6 months
    • Other Name:
    • AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1)
    • Detection Method:
    • Colorimetric
    • Background:
    • catalytic activity:ATP + a protein = ADP + a phosphoprotein.,enzyme regulation:Stimulated by clathrin.,function:Phosphorylates the AP2M1/mu2 subunit of the adaptor protein complex 2 (AP-2). May play a role in regulating aspects of clathrin-mediated endocytosis.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,subcellular location:Active when found in clathrin-coated pits at the plasma membrane.,subunit:Interacts with alpha-adaptin and AP-2.,
    • Function:
    • protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, phosphorylation,
    • Subcellular Location:
    • Cell membrane ; Peripheral membrane protein . Membrane, clathrin-coated pit . Cell junction, synapse, presynapse . Active when found in clathrin-coated pits at the plasma membrane. In neuronal cells, enriched at presynaptic terminals. In non-neuronal cells, enriched at leading edge of migrating cells. .
    • Expression:
    • Detected in brain, heart and liver. Isoform 1 is the predominant isoform in brain.