Total AP-2γ Cell-Based Colorimetric ELISA Kit
- Catalog No.:KA3841C
- Applications:ELISA
- Reactivity:Human;Mouse;Rat
- Gene Name:
- TFAP2C
- Human Gene Id:
- 7022
- Human Swiss Prot No:
- Q92754
- Mouse Swiss Prot No:
- Q61312
- Storage Stability:
- 2-8°C/6 months
- Other Name:
- Transcription factor AP-2 gamma (AP2-gamma) (Activating enhancer-binding protein 2 gamma) (Transcription factor ERF-1)
- Detection Method:
- Colorimetric
- Background:
- domain:The WW-binding motif mediates interaction with WWOX.,function:Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC.,induction:During retinoic acid-mediated differentiation.,online information:Activatin protein 2 entry,PTM:Sumoylated on Lys-10; which inhibits transcriptional activity.,similarity:Belongs to the AP-2 family.,subunit:Binds DNA as a dimer. Can form homodimers or heterodimers with other AP-2 family members (By similarity). Interacts with WWOX. Interacts with CITED4. Interacts with UBE2I.,
- Function:
- transcription, regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter,cell-cell signaling, regulation of transcription, regulation of RNA metabolic process,
- Subcellular Location:
- Nucleus .
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