Total THC2 Cell-Based Colorimetric ELISA Kit
- Catalog No.:KA3861C
- Applications:ELISA
- Reactivity:Human;Mouse
- Gene Name:
- MASTL
- Human Gene Id:
- 84930
- Human Swiss Prot No:
- Q96GX5
- Mouse Swiss Prot No:
- Q8C0P0
- Storage Stability:
- 2-8°C/6 months
- Other Name:
- Serine/threonine-protein kinase greatwall (GW) (GWL) (hGWL) (EC 2.7.11.1) (Microtubule-associated serine/threonine-protein kinase-like) (MAST-L)
- Detection Method:
- Colorimetric
- Background:
- catalytic activity:ATP + a protein = ADP + a phosphoprotein.,disease:Defects in MASTL are the cause of thrombocytopenia type 2 (THC2) [MIM:188000]. Thrombocytopenia is defined by a decrease in the number of platelets in circulating blood, resulting in the potential for increased bleeding and decreased ability for clotting.,function:Putative serine/threonine kinase which may be involved in megakaryocyte differentiation.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 1 protein kinase domain.,
- Function:
- protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, phosphorylation,
- Subcellular Location:
- Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Nucleus . Cleavage furrow . During interphase is mainly nuclear, upon nuclear envelope breakdown localizes at the cytoplasm and during mitosis at the centrosomes. Upon mitotic exit moves to the cleavage furrow. .
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