Total RNase Z2 Cell-Based Colorimetric ELISA Kit

  • Catalog No.：KA3879C
  • Applications：ELISA
  • Reactivity：Human
    • Gene Name：
    • ELAC2
    • Human Swiss Prot No：
    • Q9BQ52
    • Mouse Swiss Prot No：
    • Q80Y81
    • Storage Stability：
    • 2-8°C/6 months
    • Other Name：
    • Zinc phosphodiesterase ELAC protein 2 (EC 3.1.26.11) (ElaC homolog protein 2) (Heredity prostate cancer protein 2) (Ribonuclease Z 2) (RNase Z 2) (tRNA 3 endonuclease 2) (tRNase Z 2)
    • Detection Method：
    • Colorimetric
    • Background：
    • catalytic activity:Endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule.,cofactor:Zinc.,disease:Defects in ELAC2 are involved in prostate cancer (CaP) [MIM:176807].,function:Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.,similarity:Belongs to the RNase Z family.,subunit:Homodimer.,tissue specificity:Widely expressed. Highly expressed in heart, placenta, liver, skeletal muscle, kidney, pancreas, testis and ovary. Weakly expressed in brain, lung, spleen, thymus, prostate, small intestine, colon and leukocytes.,
    • Function：
    • RNA processing, tRNA metabolic process, tRNA processing, ncRNA processing, ncRNA metabolic process,
    • Subcellular Location：
    • Mitochondrion . Mitochondrion matrix, mitochondrion nucleoid . Nucleus . Mainly mitochondrial.
    • Expression：
    • Widely expressed. Highly expressed in heart, placenta, liver, skeletal muscle, kidney, pancreas, testis and ovary. Weakly expressed in brain, lung, spleen, thymus, prostate, small intestine, colon and leukocytes.

    Attributes

    • Code：
    • KA3879C
    • Size
    • 96 / well
    • Price$：
    • 330
    • Delivery：
    • 2024-12-09
    Order

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