Total CYP2C8/9/18/19 Cell-Based Colorimetric ELISA Kit
- Catalog No.:KA3888C
- Applications:ELISA
- Reactivity:Human
- Gene Name:
- CYP2C8/9/18/19
- Human Swiss Prot No:
- P10632/P11712/P33260/P33261
- Storage Stability:
- 2-8°C/6 months
- Detection Method:
- Colorimetric
- Background:
- catalytic activity:RH + reduced flavoprotein + O(2) = ROH + oxidized flavoprotein + H(2)O.,caution:Alternative splicing has been shown to occur but the shorter forms are believed to be non-functional.,cofactor:Heme group.,function:Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. In the epoxidation of arachidonic acid it generates only 14,15- and 11,12-cis-epoxyeicosatrienoic acids. It is the principal enzyme responsible for the metabolism the anti-cancer drug paclitaxel (taxol).,induction:By phenobarbital.,online information:CYP2C8 alleles,similarity:Belongs to the cytochrome P450 family.,
- Function:
- oxidation reduction,
- Subcellular Location:
- Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
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