Total CYP2J2 Cell-Based Colorimetric ELISA Kit
- Catalog No.:KA3892C
- Applications:ELISA
- Reactivity:Human
- Gene Name:
- CYP2J2
- Human Gene Id:
- 1573
- Human Swiss Prot No:
- P51589
- Storage Stability:
- 2-8°C/6 months
- Other Name:
- Cytochrome P450 2J2 (EC 1.14.14.1) (Arachidonic acid epoxygenase) (CYPIIJ2)
- Detection Method:
- Colorimetric
- Background:
- catalytic activity:RH + reduced flavoprotein + O(2) = ROH + oxidized flavoprotein + H(2)O.,cofactor:Heme group.,function:This enzyme metabolizes arachidonic acid predominantly via a NADPH-dependent olefin epoxidation to all four regioisomeric cis-epoxyeicosatrienoic acids. One of the predominant enzymes responsible for the epoxidation of endogenous cardiac arachidonic acid pools.,online information:CYP2J2 alleles,similarity:Belongs to the cytochrome P450 family.,tissue specificity:Highly expressed in heart, present at lower levels in liver, ileum, jejunum, colon, and kidney.,
- Function:
- fatty acid metabolic process, icosanoid metabolic process, regulation of heart contraction, unsaturated fatty acid metabolic process, regulation of system process, oxidation reduction,
- Subcellular Location:
- Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane ; Peripheral membrane protein.
- Expression:
- Highly expressed in heart, present at lower levels in liver, kidney and skeletal muscle (at protein level).
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