Total CYP4F2 Cell-Based Colorimetric ELISA Kit
- Catalog No.:KA3901C
- Applications:ELISA
- Reactivity:Human
- Gene Name:
- CYP4F2
- Human Gene Id:
- 8529
- Human Swiss Prot No:
- P78329
- Storage Stability:
- 2-8°C/6 months
- Other Name:
- Leukotriene-B(4) omega-hydroxylase 1 (EC 1.14.13.30) (CYPIVF2) (Cytochrome P450 4F2) (Cytochrome P450-LTB-omega) (Leukotriene-B(4) 20-monooxygenase 1)
- Detection Method:
- Colorimetric
- Background:
- catalytic activity:(6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate + NADPH + O(2) = (6Z,8E,10E,14Z)-(5S,12R)-5,12,20-trihydroxyicosa-6,8,10,14-tetraenoate + NADP(+) + H(2)O.,cofactor:Heme group.,function:Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.,similarity:Belongs to the cytochrome P450 family.,tissue specificity:Liver.,
- Function:
- fatty acid metabolic process, icosanoid metabolic process, leukotriene metabolic process, unsaturated fatty acid metabolic process, cellular alkene metabolic process, oxidation reduction,
- Subcellular Location:
- Microsome membrane ; Peripheral membrane protein . Endoplasmic reticulum membrane ; Peripheral membrane protein .
- Expression:
- Liver. Also present in kidney: specifically expressed in the S2 and S3 segments of proximal tubules in cortex and outer medulla (PubMed:10660572).
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