Cleaved-Integrin α5 HC (F42) Cell-Based Colorimetric ELISA Kit
- Catalog No.:KA3960C
- Applications:ELISA
- Reactivity:Human;Mouse
- Gene Name:
- ITGA5
- Human Gene Id:
- 3678
- Human Swiss Prot No:
- P08648
- Mouse Swiss Prot No:
- P11688
- Storage Stability:
- 2-8°C/6 months
- Other Name:
- Integrin alpha-5 (CD49 antigen-like family member E) (Fibronectin receptor subunit alpha) (Integrin alpha-F) (VLA-5) (CD antigen CD49e) [Cleaved into: Integrin alpha-5 heavy chain;Integrin alpha-5 light chain]
- Detection Method:
- Colorimetric
- Background:
- function:Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.,similarity:Belongs to the integrin alpha chain family.,similarity:Contains 7 FG-GAP repeats.,subunit:Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of an heavy and a light chain linked by a disulfide bond. Alpha-5 associates with beta-1. Interacts with HPS5 and NISCH. Interacts with HIV-1 Tat. Interacts with RAB21.,
- Function:
- cell motion, cell-substrate junction assembly, cell adhesion, heterophilic cell adhesion, leukocyte adhesion, cell surface receptor linked signal transduction, integrin-mediated signaling pathway, behavior, learning or memory, memory,response to wounding, cell-cell adhesion, cell migration, biological adhesion, cell adhesion mediated by integrin, cell-cell adhesion mediated by integrin, cell junction assembly, cell junction organization, wound healing, spreading of epidermal cells, wound healing, cell motility, neurological system process, cognition, localization of cell,
- Subcellular Location:
- Membrane; Single-pass type I membrane protein. Cell junction, focal adhesion . Cell surface .
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