Total ICAM-1 Cell-Based Colorimetric ELISA Kit

  • Catalog No.：KA4126C
  • Applications：ELISA
  • Reactivity：Human
    • Gene Name：
    • ICAM1
    • Human Gene Id：
    • 3383
    • Human Swiss Prot No：
    • P05362
    • Mouse Swiss Prot No：
    • P13597
    • Storage Stability：
    • 2-8°C/6 months
    • Other Name：
    • Intercellular adhesion molecule 1 (ICAM-1) (Major group rhinovirus receptor) (CD antigen CD54)
    • Detection Method：
    • Colorimetric
    • Background：
    • function:ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.,online information:ICAM-1,online information:Icosahedral capsid structure,online information:Intercellular adhesion molecule entry,polymorphism:Homozygotes with ICAM1-Kalifi Met-56 seem to have an increased risk for cerebral malaria.,PTM:Monoubiquitinated, which is promoted by MARCH9 and leads to endocytosis.,similarity:Belongs to the immunoglobulin superfamily. ICAM family.,similarity:Contains 5 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Homodimer (Probable). Interacts with human herpesvirus 8 MIR2 protein (Probable). Interacts with MUC1 and promotes cell aggregation in epithelial cells. Interacts with SGEF. Binds to coxsackievirus A21 capsid proteins and acts as a receptor for this virus.,
    • Function：
    • cell activation, regulation of leukocyte mediated cytotoxicity, adaptive immune response, immune effector process, cell activation during immune response, lymphocyte activation during immune response, T cell activation during immune response, T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell,leukocyte activation during immune response, leukocyte mediated immunity, lymphocyte mediated immunity, T cell mediated immunity, T cell antigen processing and presentation, adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, positive regulation of immune system process, regulation of leukocyte migration, positive regulation of leukocyte migration, regulation of cellular extravasation, positive regulation of cellular extravasation, regulation of immune effector process, cel
    • Subcellular Location：
    • Membrane; Single-pass type I membrane protein.

    Attributes

    • Code：
    • KA4126C
    • Size
    • 96 / well
    • Price$：
    • 330
    • Delivery：
    • 2024-08-01
    Order

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