Total p47 phox Cell-Based Colorimetric ELISA Kit

  • Catalog No.：KA4210C
  • Applications：ELISA
  • Reactivity：Human
    • Gene Name：
    • NCF1
    • Human Swiss Prot No：
    • P14598
    • Mouse Swiss Prot No：
    • Q09014
    • Storage Stability：
    • 2-8°C/6 months
    • Other Name：
    • Neutrophil cytosol factor 1 (NCF-1) (47 kDa autosomal chronic granulomatous disease protein) (47 kDa neutrophil oxidase factor) (NCF-47K) (Neutrophil NADPH oxidase factor 1) (Nox organizer 2) (Nox-organizing protein 2) (SH3 and PX domain-containing protein 1A) (p47-phox)
    • Detection Method：
    • Colorimetric
    • Background：
    • disease:Defects in NCF1 are the cause of chronic granulomatous disease autosomal recessive cytochrome-b-positive type 1 (CGD1) [MIM:233700]. Chronic granulomatous disease is a genetically heterogeneous disorder characterized by the inability of neutrophils and phagocytes to kill microbes that they have ingested. Patients suffer from life-threatening bacterial/fungal infections.,function:NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production).,online information:NCF1 deficiency database,similarity:Contains 1 PX (phox homology) domain.,similarity:Contains 2 SH3 domains.,subunit:Interacts with NOXA1.,
    • Function：
    • oxygen and reactive oxygen species metabolic process, superoxide metabolic process, defense response, immune response, cellular defense response, superoxide anion generation, innate immune response, respiratory burst,
    • Subcellular Location：
    • Cytoplasm, cytosol . Membrane ; Peripheral membrane protein ; Cytoplasmic side .
    • Expression：
    • Detected in peripheral blood monocytes and neutrophils (at protein level).

    Attributes

    • Code：
    • KA4210C
    • Size
    • 96 / well
    • Price$：
    • 330
    • Delivery：
    • 2025-01-10
    Order

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