Total PBK/TOPK Cell-Based Colorimetric ELISA Kit

  • Catalog No.：KA4222C
  • Applications：ELISA
  • Reactivity：Human
    • Gene Name：
    • PBK
    • Human Swiss Prot No：
    • Q96KB5
    • Mouse Swiss Prot No：
    • Q9JJ78
    • Storage Stability：
    • 2-8°C/6 months
    • Other Name：
    • Lymphokine-activated killer T-cell-originated protein kinase (EC 2.7.12.2) (Cancer/testis antigen 84) (CT84) (MAPKK-like protein kinase) (Nori-3) (PDZ-binding kinase) (Spermatogenesis-related protein kinase) (SPK) (T-LAK cell-originated protein kinase)
    • Detection Method：
    • Colorimetric
    • Background：
    • catalytic activity:ATP + a protein = ADP + a phosphoprotein.,enzyme regulation:Activated by phosphorylation.,function:Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage.,PTM:Phosphorylated; in a cell-cycle dependent manner at mitosis.,similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase kinase subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with DLG1 and TP53.,tissue specificity:Expressed in the testis and placenta. In the testis, restrictedly expressed in outer cell layer of seminiferous tubules.,
    • Function：
    • M phase of mitotic cell cycle, mitotic cell cycle, M phase, nuclear division, protein amino acid phosphorylation,phosphorus metabolic process, phosphate metabolic process, cell cycle, mitosis, phosphorylation, cell cycle process,cell cycle phase, organelle fission,
    • Expression：
    • Expressed in the testis and placenta. In the testis, restrictedly expressed in outer cell layer of seminiferous tubules.

    Attributes

    • Code：
    • KA4222C
    • Size
    • 96 / well
    • Price$：
    • 330
    • Delivery：
    • 2024-12-08
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