Total PKA-R2β Cell-Based Colorimetric ELISA Kit

  • Catalog No.：KA4235C
  • Applications：ELISA
  • Reactivity：Human;Mouse;Rat
    • Gene Name：
    • PRKAR2B
    • Human Gene Id：
    • 5577
    • Human Swiss Prot No：
    • P31323
    • Mouse Swiss Prot No：
    • P31324
    • Storage Stability：
    • 2-8°C/6 months
    • Other Name：
    • cAMP-dependent protein kinase type II-beta regulatory subunit
    • Detection Method：
    • Colorimetric
    • Background：
    • function:Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase.,PTM:Phosphorylated by the activated catalytic chain.,similarity:Belongs to the cAMP-dependent kinase regulatory chain family.,similarity:Contains 2 cyclic nucleotide-binding domains.,subunit:The inactive form of the enzyme is composed of two regulatory chains and two catalytic chains. Activation by cAMP produces two active catalytic monomers and a regulatory dimer that binds four cAMP molecules.,tissue specificity:Four types of regulatory chains are found: I-alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible.,
    • Function：
    • regulation of protein amino acid phosphorylation, fatty acid metabolic process, intracellular signaling cascade,behavior, learning or memory, learning, response to endogenous stimulus, response to hormone stimulus, hormone-mediated signaling, response to organic substance, regulation of phosphate metabolic process, regulation of protein modification process, activation of protein kinase activity, regulation of cellular protein metabolic process, cellular response to hormone stimulus, positive regulation of kinase activity, activation of protein kinase A activity, regulation of phosphorylation, positive regulation of catalytic activity, regulation of kinase activity, positive regulation of molecular function, regulation of protein kinase activity, positive regulation of protein kinase activity, neurological system process, cognition, regulation of phosphorus metabolic process, regulation
    • Subcellular Location：
    • Cytoplasm . Cell membrane . Colocalizes with PJA2 in the cytoplasm and at the cell membrane.
    • Expression：
    • Four types of regulatory chains are found: I-alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible.

    Attributes

    • Code：
    • KA4235C
    • Size
    • 96 / well
    • Price$：
    • 330
    • Delivery：
    • 2024-05-23
    Order

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