• Gene Name：
• PLCB3

• Human Gene Id：
• 5331

• Human Swiss Prot No：
• Q01970

• Mouse Swiss Prot No：
• P51432

• Rat Swiss Prot No：
• Q99JE6

• Storage Stability：
• 2-8°C/6 months

• Other Name：
• 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-3) (Phospholipase C-beta-3) (PLC-beta-3)

• Detection Method：
• Colorimetric

• Background：
• catalytic activity:1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol.,cofactor:Calcium.,function:The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.,similarity:Contains 1 C2 domain.,similarity:Contains 1 PI-PLC X-box domain.,similarity:Contains 1 PI-PLC Y-box domain.,subunit:Interacts with SHANK2 (By similarity). Interacts with LPAR2.,

• Function：
• phospholipid metabolic process, intracellular signaling cascade, phospholipid catabolic process, lipid catabolic process,organophosphate metabolic process, cellular lipid catabolic process,

• Subcellular Location：
• Cytoplasm . Membrane . Nucleus . And particulate fractions. .

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