Total RFA2 Cell-Based Colorimetric ELISA Kit

  • Catalog No.：KA4267C
  • Applications：ELISA
  • Reactivity：Human;Mouse;
    • Gene Name：
    • RFA2
    • Human Gene Id：
    • 6118
    • Human Swiss Prot No：
    • P15927
    • Mouse Swiss Prot No：
    • Q62193
    • Storage Stability：
    • 2-8°C/6 months
    • Other Name：
    • Replication protein A 32 kDa subunit (RP-A p32) (Replication factor A protein 2) (RF-A protein 2) (Replication protein A 34 kDa subunit) (RP-A p34)
    • Detection Method：
    • Colorimetric
    • Background：
    • function:Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions.,PTM:Phosphorylated in a cell-cycle-dependent manner (from the S phase until mitosis). Phosphorylated by ATR upon DNA damage, which promotes its translocation to nuclear foci. Can be phosphorylated in vitro by PRKDC/DNA-PK in the presence of Ku and DNA, and by CDC2.,subcellular location:Also present in PML nuclear bodies. Redistributes to discrete nuclear foci upon DNA damage.,subunit:Heterotrimer of 70, 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Binds to SERTAD3/RBT1. Interacts with TIPIN.,
    • Function：
    • nucleotide-excision repair, DNA damage removal, DNA metabolic process, DNA replication, DNA-dependent DNA replication, DNA repair, nucleotide-excision repair, nucleotide-excision repair, DNA gap filling, DNA catabolic process,response to DNA damage stimulus, macromolecule catabolic process, cellular response to stress, cellular macromolecule catabolic process,
    • Subcellular Location：
    • Nucleus . Nucleus, PML body . Redistributes to discrete nuclear foci upon DNA damage in an ATR-dependent manner. .

    Attributes

    • Code：
    • KA4267C
    • Size
    • 96 / well
    • Price$：
    • 330
    • Delivery：
    • 2024-05-22
    Order

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