Total VE-Cadherin Cell-Based Colorimetric ELISA Kit
- Catalog No.:KA4320C
- Applications:ELISA
- Reactivity:Human;Mouse
- Gene Name:
- CDH5
- Human Gene Id:
- 1003
- Human Swiss Prot No:
- P33151
- Mouse Swiss Prot No:
- P55284
- Storage Stability:
- 2-8°C/6 months
- Other Name:
- Cadherin-5 (7B4 antigen) (Vascular endothelial cadherin) (VE-cadherin) (CD antigen CD144)
- Detection Method:
- Colorimetric
- Background:
- function:Cadherins are calcium dependent cell adhesion proteins.,function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton.,similarity:Contains 5 cadherin domains.,subcellular location:Found at cell-cell boundaries and probably at cell-matrix boundaries.,tissue specificity:Endothelial tissues and brain.,
- Function:
- blood vessel development, vasculature development, blood vessel maturation, cell adhesion, homophilic cell adhesion,negative regulation of cell proliferation, cell-cell adhesion, developmental maturation, biological adhesion, regulation of cell proliferation,
- Subcellular Location:
- Cell junction . Cell membrane ; Single-pass type I membrane protein . Found at cell-cell boundaries and probably at cell-matrix boundaries. KRIT1 and CDH5 reciprocally regulate their localization to endothelial cell-cell junctions. .
- Expression:
- Endothelial tissues and brain.
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