Total K6PP Cell-Based Colorimetric ELISA Kit
- Catalog No.:KA4344C
- Applications:ELISA
- Reactivity:Human;Mouse;Rat
- Gene Name:
- K6PP
- Human Gene Id:
- 5214
- Human Swiss Prot No:
- Q01813
- Mouse Swiss Prot No:
- Q9WUA3
- Rat Swiss Prot No:
- P47860
- Storage Stability:
- 2-8°C/6 months
- Other Name:
- 6-phosphofructokinase type C (EC 2.7.1.11) (6-phosphofructokinase, platelet type) (Phosphofructo-1-kinase isozyme C) (PFK-C) (Phosphofructokinase 1) (Phosphohexokinase)
- Detection Method:
- Colorimetric
- Background:
- catalytic activity:ATP + D-fructose 6-phosphate = ADP + D-fructose 1,6-bisphosphate.,cofactor:Magnesium.,enzyme regulation:Allosteric enzyme activated by ADP, AMP, or fructose bisphosphate and inhibited by ATP or citrate.,miscellaneous:In human PFK exists as a system of 3 types of subunits, PFKM (muscle), PFKL (liver) and PFKP (platelet) isoenzymes.,pathway:Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4.,similarity:Belongs to the phosphofructokinase family. Two domains subfamily.,subunit:Tetramer. Muscle is M4, liver is L4, and red cell is M3L, M2L2, or ML3. A subunit composition with a higher proportion of platelet type subunits is found in platelets, brain and fibroblasts.,
- Function:
- monosaccharide metabolic process, fructose metabolic process, fructose 6-phosphate metabolic process, glucose metabolic process, glucose catabolic process, generation of precursor metabolites and energy, glycolysis, protein complex assembly, carbohydrate catabolic process, hexose metabolic process, hexose catabolic process, fructose 1,6-bisphosphate metabolic process, macromolecular complex subunit organization, cellular carbohydrate catabolic process, alcohol catabolic process, monosaccharide catabolic process, protein oligomerization, protein homooligomerization, protein tetramerization, protein homotetramerization, macromolecular complex assembly,protein complex biogenesis,
- Subcellular Location:
- Cytoplasm .
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