• Gene Name：
• TFPI

• Protein Name：
• Tissue factor pathway inhibitor

• Human Gene Id：
• 7035

• Human Swiss Prot No：
• P10646

• Mouse Swiss Prot No：
• O54819

• Specificity：
• Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma

• Storage Stability：
• 2-8°C/6 months

• Other Name：
• TFPI;LACI;TFPI1;Tissue factor pathway inhibitor;TFPI;Extrinsic pathway inhibitor;EPI;Lipoprotein-associated coagulation inhibitor;LACI

• Detection Method：
• Colorimetric

• Background：
• domain:This inhibitor contains three inhibitory domains. The first domain interacts with VIIa and TF, the second one with Xa.,function:Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma.,online information:TFPI entry,PTM:O-glycosylated.,similarity:Contains 2 BPTI/Kunitz inhibitor domains.,similarity:Contains 3 BPTI/Kunitz inhibitor domains.,tissue specificity:Mostly in endothelial cells.,

• Function：
• blood coagulation, blood coagulation, extrinsic pathway, hemostasis, response to wounding, wound healing,coagulation, regulation of body fluid levels,

• Subcellular Location：
• [Isoform Alpha]: Secreted.; [Isoform Beta]: Microsome membrane ; Lipid-anchor, GPI-anchor .

• Expression：
• Mostly in endothelial cells.

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