ACSS2 (Acetyl Lys418) rabbit pAb

  • Catalog No.:YK0097
  • Applications:WB;ELISA
  • Reactivity:Human;Mouse
    • Target:
    • ACSS2
    • Fields:
    • >>Glycolysis / Gluconeogenesis;>>Pyruvate metabolism;>>Glyoxylate and dicarboxylate metabolism;>>Propanoate metabolism;>>Metabolic pathways;>>Carbon metabolism
    • Gene Name:
    • ACSS2 ACAS2
    • Protein Name:
    • ACSS2 (Acetyl Lys418)
    • Human Swiss Prot No:
    • Q9NR19
    • Mouse Swiss Prot No:
    • Q9QXG4
    • Immunogen:
    • Synthesized peptide derived from human ACSS2 (Acetyl Lys418)
    • Specificity:
    • This antibody detects endogenous levels of Human,Mouse ACSS2 (Acetyl Lys418)
    • Formulation:
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • Source:
    • Polyclonal, Rabbit,IgG
    • Dilution:
    • WB 1:1000-2000 ELISA 1:5000-20000
    • Purification:
    • The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
    • Concentration:
    • 1 mg/ml
    • Storage Stability:
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • Other Name:
    • Acetyl-coenzyme A synthetase, cytoplasmic (EC 6.2.1.1;Acetate--CoA ligase;Acetyl-CoA synthetase;ACS;AceCS;Acyl-CoA synthetase short-chain family member 2;Acyl-activating enzyme)
    • Observed Band(KD):
    • 80kD
    • Background:
    • This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009],
    • Function:
    • catalytic activity:ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA.,function:Activates acetate so that it can be used for lipid synthesis or for energy generation.,similarity:Belongs to the ATP-dependent AMP-binding enzyme family.,subunit:Monomer.,
    • Subcellular Location:
    • Cytoplasm, cytosol .