c-Myb (Acetyl Lys480) rabbit pAb
- Catalog No.:YK0158
- Applications:WB;ELISA
- Reactivity:Human;Mouse
- Target:
- c-Myb
- Fields:
- >>PI3K-Akt signaling pathway
- Gene Name:
- MYB
- Protein Name:
- c-Myb (Acetyl Lys480)
- Human Gene Id:
- 4602
- Human Swiss Prot No:
- P10242
- Mouse Gene Id:
- 17863
- Mouse Swiss Prot No:
- P06876
- Immunogen:
- Synthesized peptide derived from human c-Myb (Acetyl Lys480)
- Specificity:
- This antibody detects endogenous levels of Human,Mouse c-Myb (Acetyl Lys480)
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:1000-2000 ELISA 1:5000-20000
- Purification:
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- Transcriptional activator Myb (Proto-oncogene c-Myb)
- Observed Band(KD):
- 70kD
- Background:
- domain:Comprised of 3 domains; an N-terminal DNA-binding domain, a centrally located transcriptional activation domain and a C-terminal domain involved in transcriptional repression.,function:Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.,PTM:Phosphorylated by NLK on multiple sites, which induces proteasomal degradation.,PTM:Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation.,similarity:Contains 3 HTH myb-type DNA-binding domains.,subunit:Binds MYBBP1A. Interacts with HIPK2, MAF and NLK.,
- Function:
- transcription, regulation of transcription, DNA-dependent, regulation of transcription, regulation of RNA metabolic process,
- Subcellular Location:
- Nucleus .
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