• Target：
• Blimp-1

• Gene Name：
• PRDM1

• Protein Name：
• PR domain zinc finger protein 1

• Human Gene Id：
• 639

• Human Swiss Prot No：
• O75626

• Mouse Gene Id：
• 12142

• Mouse Swiss Prot No：
• Q60636

• Immunogen：
• Purified recombinant fragment of human Blimp-1 expressed in E. Coli.

• Specificity：
• Blimp-1 Monoclonal Antibody detects endogenous levels of Blimp-1 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Monoclonal, Mouse

• Dilution：
• WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

• Purification：
• Affinity purification

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• PRDM1;BLIMP1;PR domain zinc finger protein 1;BLIMP-1;Beta-interferon gene positive regulatory domain I-binding factor;PR domain-containing protein 1;Positive regulatory domain I-binding factor 1;PRDI-BF1;PRDI-binding factor 1

• Molecular Weight(Da)：
• 92kD

• References：
• 1. Nat Cell Biol. 2006 Jun;8(6):623-30.
  2. Int J Hematol. 2007 Dec;86(5):429-37.
  3. Nat Genet. 2008 Aug;40(8):955-62.

• Background：
• This gene encodes a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported. [provided by RefSeq, Jul 2008],

• Function：
• function:Transcriptional repressor that binds specifically to the PRDI element in the promoter of the beta-interferon gene. Drives the maturation of B-lymphocytes into Ig secreting cells.,similarity:Contains 1 SET domain.,similarity:Contains 4 C2H2-type zinc fingers.,subunit:Interacts with PRMT5.,

• Subcellular Location：
• Nucleus . Cytoplasm .

• Expression：
• PCR rescued clones,Stomach,

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