• Target：
• CD15

• Fields：
• >>Mannose type O-glycan biosynthesis;>>Glycosphingolipid biosynthesis - lacto and neolacto series;>>Metabolic pathways

• Gene Name：
• FUT4

• Protein Name：
• Alpha-(1,3)-fucosyltransferase

• Human Gene Id：
• 2526

• Human Swiss Prot No：
• P22083

• Mouse Swiss Prot No：
• Q11127

• Immunogen：
• Synthesized peptide of human CD15.

• Specificity：
• CD15 Monoclonal Antibody detects endogenous levels of CD15 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Monoclonal, Mouse

• Dilution：
• IHC 1:200 - 1:1000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

• Purification：
• Affinity purification

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• FUT4;ELFT;FCT3A;Alpha-(1;3)-fucosyltransferase;ELAM-1 ligand fucosyltransferase;Fucosyltransferase 4;Fucosyltransferase IV;Fuc-TIV;FucT-IV;Galactoside 3-L-fucosyltransferase

• References：
• 1. Cancer Cell. 2009 Feb 3;15(2):135-47.
  2. Biochim Biophys Acta. 2008 Feb;1783(2):287-96.

• Background：
• The product of this gene transfers fucose to N-acetyllactosamine polysaccharides to generate fucosylated carbohydrate structures. It catalyzes the synthesis of the non-sialylated antigen, Lewis x (CD15). [provided by RefSeq, Jan 2009],

• Function：
• caution:It is uncertain whether Met-1 or Met-126 is the initiator.,function:May catalyze alpha-1,3 glycosidic linkages involved in the expression of Lewis X/SSEA-1 and VIM-2 antigens.,online information:Fucosyltransferase 4,online information:GlycoGene database,pathway:Protein modification; protein glycosylation.,similarity:Belongs to the glycosyltransferase 10 family.,subcellular location:Membrane-bound form in trans cisternae of Golgi.,

• Subcellular Location：
• Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Membrane-bound form in trans cisternae of Golgi.

• Expression：
• [Isoform Short]: Expressed at low levels in bone marrow-derived mesenchymal stem cells. ; Expressed in cord blood immature promyelocytes and in peripheral blood myeloid and lymphoid cell populations.

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