• Target：
• CD69

• Gene Name：
• CD69

• Protein Name：
• Early activation antigen CD69

• Human Gene Id：
• 969

• Human Swiss Prot No：
• Q07108

• Mouse Swiss Prot No：
• P37217

• Immunogen：
• Purified recombinant fragment of human CD69 expressed in E. Coli.

• Specificity：
• CD69 Monoclonal Antibody detects endogenous levels of CD69 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Monoclonal, Mouse

• Dilution：
• WB 1:500 - 1:2000. IHC 1:200 - 1:1000. Flow cytometry: 1:200 - 1:400. ELISA: 1:10000.. IF 1:50-200

• Purification：
• Affinity purification

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• CD69;CLEC2C;Early activation antigen CD69;Activation inducer molecule;AIM;BL-AC/P26;C-type lectin domain family 2 member C;EA1;Early T-cell activation antigen p60;GP32/28;Leukocyte surface antigen Leu-23;MLR-3;CD antigen CD69

• Molecular Weight(Da)：
• 23kD

• References：
• 1. EMBO J. 1997 Feb 17;16(4):673-84.
  2. Cell Immunol. 2002 Nov;220(1):20-9.
  3. Arch Biochem Biophys. 2005 Jun 1;438(1):11-20.

• Background：
• This gene encodes a member of the calcium dependent lectin superfamily of type II transmembrane receptors. Expression of the encoded protein is induced upon activation of T lymphocytes, and may play a role in proliferation. Furthermore, the protein may act to transmit signals in natural killer cells and platelets. [provided by RefSeq, Aug 2011],

• Function：
• developmental stage:Earliest inducible cell surface glycoprotein acquired during lymphoid activation.,function:Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets.,induction:By antigens, mitogens or activators of PKC on the surface of T and B-lymphocytes. By interaction of IL-2 with the p75 IL-2R on the surface of NK cells.,online information:CD69,PTM:Constitutive Ser/Thr phosphorylation in both mature thymocytes and activated T-lymphocytes.,similarity:Contains 1 C-type lectin domain.,subunit:Homodimer; disulfide-linked.,tissue specificity:Expressed on the surface of activated T-cells, B-cells, natural killer cells, neutrophils, eosinophils, epidermal Langerhans cells and platelets.,

• Subcellular Location：
• Membrane; Single-pass type II membrane protein.

• Expression：
• Expressed on the surface of activated T-cells, B-cells, natural killer cells, neutrophils, eosinophils, epidermal Langerhans cells and platelets.

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