• Target：
• Cerberus

• Fields：
• >>Wnt signaling pathway

• Gene Name：
• CER1

• Protein Name：
• Cerberus

• Human Gene Id：
• 9350

• Human Swiss Prot No：
• O95813

• Mouse Swiss Prot No：
• O55233

• Immunogen：
• Purified recombinant fragment of human Cerberus expressed in E. Coli.

• Specificity：
• Cerberus Monoclonal Antibody detects endogenous levels of Cerberus protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Monoclonal, Mouse

• Dilution：
• WB 1:500 - 1:2000. IHC 1:200 - 1:1000. ELISA: 1:10000.. IF 1:50-200

• Purification：
• Affinity purification

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• CER1;DAND4;Cerberus;Cerberus-related protein;DAN domain family member 4

• Molecular Weight(Da)：
• 30kD

• References：
• 1. Dev Biol. 1998 Feb 15;194(2):135-51.
  2. Growth Factors. 2004 Dec;22(4):233-41.
  3. PLoS One. 2009;4(4):e5302.

• Background：
• This gene encodes a cytokine member of the cysteine knot superfamily, characterized by nine conserved cysteines and a cysteine knot region. The cerberus-related cytokines, together with Dan and DRM/Gremlin, represent a group of bone morphogenetic protein (BMP) antagonists that can bind directly to BMPs and inhibit their activity. [provided by RefSeq, Jul 2008],

• Function：
• function:Cytokine that may play a role in anterior neural induction and somite formation during embryogenesis in part through a BMP-inhibitory mechanism. Can regulate Nodal signaling during gastrulation as well as the formation and patterning of the primitive streak.,PTM:N-glycosylated.,sequence caution:Translated as Ser.,similarity:Belongs to the DAN family.,similarity:Contains 1 CTCK (C-terminal cystine knot-like) domain.,subunit:Forms monomers and predominantly dimers.,

• Subcellular Location：
• Secreted .

• Expression：
• Blood,PCR rescued clones,

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