Fibulin-2 Monoclonal Antibody

    • Catalog No.:YM0271
    • Applications:WB;ELISA
    • Reactivity:Human
      • Target:
      • Fibulin-2
      • Gene Name:
      • FBLN2
      • Protein Name:
      • Fibulin-2
      • Human Gene Id:
      • 2199
      • Human Swiss Prot No:
      • P98095
      • Mouse Swiss Prot No:
      • P37889
      • Immunogen:
      • Purified recombinant fragment of Fibulin-2 (aa180-440) expressed in E. Coli.
      • Specificity:
      • Fibulin-2 Monoclonal Antibody detects endogenous levels of Fibulin-2 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Monoclonal, Mouse
      • Dilution:
      • WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
      • Purification:
      • Affinity purification
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • FBLN2;Fibulin-2;FIBL-2
      • Molecular Weight(Da):
      • 127kD
      • References:
      • 1. J Biol Chem. 1996 Aug 9;271(32):19489-96.
        2. Eur J Hum Genet. 1996;4(5):292-5.
        3. J Invest Dermatol. 1999 Jan;112(1):97-101.
        4. Br J Dermatol. 2001 Aug;145(2):217-22.
      • Background:
      • This gene encodes an extracellular matrix protein, which belongs to the fibulin family. This protein binds various extracellular ligands and calcium. It may play a role during organ development, in particular, during the differentiation of heart, skeletal and neuronal structures. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
      • Function:
      • developmental stage:Widely expressed during embryonic development. Primarily detected within the neuropithelium, spinal ganglia and peripheral nerves.,function:Its binding to fibronectin and some other ligands is calcium dependent.,similarity:Belongs to the fibulin family.,similarity:Contains 11 EGF-like domains.,similarity:Contains 3 anaphylatoxin-like domains.,subunit:Homotrimer; disulfide-linked. Interacts with LAMA2.,tissue specificity:Component of both basement membranes and other connective tissues. Expressed in heart, placenta and ovary.,
      • Subcellular Location:
      • Secreted, extracellular space, extracellular matrix.
      • Expression:
      • Component of both basement membranes and other connective tissues. Expressed in heart, placenta and ovary.
      • Products Images
      • Western Blot analysis using Fibulin-2 Monoclonal Antibody against truncated FBLN2-Trx recombinant protein (1) and truncated FBLN2 (aa28-444)-hIgGFc transfected COS7 cell lysate(2).