Fibulin-2 Monoclonal Antibody
- Catalog No.:YM0271
- Applications:WB;ELISA
- Reactivity:Human
- Target:
- Fibulin-2
- Gene Name:
- FBLN2
- Protein Name:
- Fibulin-2
- Human Gene Id:
- 2199
- Human Swiss Prot No:
- P98095
- Mouse Swiss Prot No:
- P37889
- Immunogen:
- Purified recombinant fragment of Fibulin-2 (aa180-440) expressed in E. Coli.
- Specificity:
- Fibulin-2 Monoclonal Antibody detects endogenous levels of Fibulin-2 protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Monoclonal, Mouse
- Dilution:
- WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
- Purification:
- Affinity purification
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- FBLN2;Fibulin-2;FIBL-2
- Molecular Weight(Da):
- 127kD
- References:
- 1. J Biol Chem. 1996 Aug 9;271(32):19489-96.
2. Eur J Hum Genet. 1996;4(5):292-5.
3. J Invest Dermatol. 1999 Jan;112(1):97-101.
4. Br J Dermatol. 2001 Aug;145(2):217-22.
- Background:
- This gene encodes an extracellular matrix protein, which belongs to the fibulin family. This protein binds various extracellular ligands and calcium. It may play a role during organ development, in particular, during the differentiation of heart, skeletal and neuronal structures. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
- Function:
- developmental stage:Widely expressed during embryonic development. Primarily detected within the neuropithelium, spinal ganglia and peripheral nerves.,function:Its binding to fibronectin and some other ligands is calcium dependent.,similarity:Belongs to the fibulin family.,similarity:Contains 11 EGF-like domains.,similarity:Contains 3 anaphylatoxin-like domains.,subunit:Homotrimer; disulfide-linked. Interacts with LAMA2.,tissue specificity:Component of both basement membranes and other connective tissues. Expressed in heart, placenta and ovary.,
- Subcellular Location:
- Secreted, extracellular space, extracellular matrix.
- Expression:
- Component of both basement membranes and other connective tissues. Expressed in heart, placenta and ovary.
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- Antibody-FAQs
- Products Images
- Western Blot analysis using Fibulin-2 Monoclonal Antibody against truncated FBLN2-Trx recombinant protein (1) and truncated FBLN2 (aa28-444)-hIgGFc transfected COS7 cell lysate(2).