• Target：
• GSK3α

• Fields：
• >>Chemokine signaling pathway;>>Dopaminergic synapse;>>Non-alcoholic fatty liver disease;>>Shigellosis

• Gene Name：
• GSK3A

• Protein Name：
• Glycogen synthase kinase-3 alpha

• Human Gene Id：
• 2931

• Human Swiss Prot No：
• P49840

• Mouse Swiss Prot No：
• Q2NL51

• Immunogen：
• Purified recombinant fragment of GSK3α expressed in E. Coli.

• Specificity：
• GSK3α Monoclonal Antibody detects endogenous levels of GSK3α protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Monoclonal, Mouse

• Dilution：
• WB 1:500 - 1:2000. IHC 1:200 - 1:1000. ELISA: 1:10000.. IF 1:50-200

• Purification：
• Affinity purification

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• GSK3A;Glycogen synthase kinase-3 alpha;GSK-3 alpha;Serine/threonine-protein kinase GSK3A

• Molecular Weight(Da)：
• 51kD

• References：
• 1. Bradley W. Doble and James R. Woodgett. J. Cell Sci., Apr 2003; 116: 1175.
  2. C. Laura Sayas , Aafke Ariaens, Bas Ponsioen. Mol. Biol. Cell, Apr 2006; 17: 1834 – 1844.

• Background：
• glycogen synthase kinase 3 alpha(GSK3A) Homo sapiens This gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease. [provided by RefSeq, Oct 2011],

• Function：
• catalytic activity:ATP + [tau protein] = ADP + [tau protein] phosphate.,function:Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Monomer.,

• Subcellular Location：
• apical dendrite;axon;beta-catenin destruction complex;cytoplasm;cytosol;mitochondrion;neuronal cell body;nucleus;postsynapse;proximal dendrite;

• Expression：
• Brain,Eye,Foreskin,Lung,Pancreas,Platelet,Testis,

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