• Target：
• TH-POK

• Gene Name：
• ZBTB7B

• Protein Name：
• Zinc finger and BTB domain-containing protein 7B

• Human Gene Id：
• 51043

• Human Swiss Prot No：
• O15156

• Mouse Swiss Prot No：
• Q64321

• Immunogen：
• Purified recombinant fragment of human TH-POK expressed in E. Coli.

• Specificity：
• TH-POK Monoclonal Antibody detects endogenous levels of TH-POK protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Monoclonal, Mouse

• Dilution：
• WB 1:500 - 1:2000. IHC 1:200 - 1:1000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

• Purification：
• Affinity purification

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• ZBTB7B;ZBTB15;ZFP67;ZNF857B;Zinc finger and BTB domain-containing protein 7B;Krueppel-related zinc finger protein cKrox;hcKrox;T-helper-inducing POZ/Krueppel-like factor;Zinc finger and BTB domain-containing protein 15;Zinc finger

• Molecular Weight(Da)：
• 58kD

• References：
• 1.Proc Natl Acad Sci U S A. 1994 Sep 27;91(20):9372-6.
  2.J Biol Chem. 2000 Sep 1;275(35):27421-38.
  3.J Cell Biochem. 2009 Aug 15;107(6):1037-45. Review.

• Background：
• This gene encodes a zinc finger-containing transcription factor that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. It also functions as a transcriptional repressor of type I collagen genes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012],

• Function：
• function:Transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. Necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. Transcriptional repressor of the collagen COL1A1 and COL1A2 genes. May also function as a repressor of fibronectin and possibly other extracellular matrix genes.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 4 C2H2-type zinc fingers.,

• Subcellular Location：
• Nucleus .

• Expression：
• Salivary gland,Skin fibroblast,Uterus,

• June 19-2018
• WESTERN IMMUNOBLOTTING PROTOCOL

• June 19-2018
• IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL

• June 19-2018
• IMMUNOFLUORESCENCE PROTOCOL

• September 08-2020
• FLOW-CYTOMEYRT-PROTOCOL

• May 20-2022
• Cell-Based ELISA│解您多样本WB检测之困扰

• July 13-2018
• CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN

• July 13-2018
• CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN

• July 13-2018
• CELL-BASED-COLORIMETRIC-ELISA-PROTOCOL-FOR-TOTAL-PROTEIN

• July 13-2018
• Antibody-FAQs