• Target：
• RRAD

• Gene Name：
• RRAD RAD

• Protein Name：
• GTP-binding protein RAD (RAD1) (Ras associated with diabetes)

• Human Gene Id：
• 6236

• Human Swiss Prot No：
• P55042

• Mouse Gene Id：
• 0

• Mouse Swiss Prot No：
• O88667

• Immunogen：
• Synthesized peptide derived from human protein. AA range: 1-100

• Specificity：
• This antibody detects endogenous levels of RRAD protein.

• Formulation：
• PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

• Source：
• Mouse, Monoclonal/IgG1, kappa

• Dilution：
• WB 1:500-2000. IF 1:100-500. ELISA 1:1000-5000

• Purification：
• Protein G

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• GTP-binding protein RAD (RAD1) (Ras associated with diabetes)

• Molecular Weight(Da)：
• 33kD

• Observed Band(KD)：
• 33kD

• Function：
• May play an important role in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca(2+) currents. Regulates voltage-dependent L-type calcium channel subunit alpha-1C trafficking to the cell membrane (By similarity). Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway. Inhibits phosphorylation and activation of CAMK2D.

• Subcellular Location：
• Membranous

• Expression：
• Most abundantly expressed in the heart. Also found in the skeletal muscle and lung. Lesser amounts in placenta and kidney. Also detected in adipose tissue. Overexpressed in muscle of type II diabetic humans.

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