CA IX (PTR2373) mouse mAb
- Catalog No.:YM6225
- Applications:IHC;ELISA
- Reactivity:Human;
- Target:
- CA IX
- Fields:
- >>Nitrogen metabolism;>>Metabolic pathways
- Gene Name:
- CA9
- Protein Name:
- Carbonic anhydrase 9
- Human Gene Id:
- 768
- Human Swiss Prot No:
- Q16790
- Mouse Gene Id:
- 230099
- Mouse Swiss Prot No:
- Q8VHB5
- Immunogen:
- Recombinant protein
- Specificity:
- This antibody detects endogenous levels of CA IX protein.
- Formulation:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
- Source:
- Mouse, Monoclonal/IgG
- Dilution:
- IHC 1:200-400. ELISA 1:500-5000
- Purification:
- The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- G250; MN; Carbonic anhydrase 9; Carbonate dehydratase IX; Carbonic anhydrase IX; CA-IX; CAIX; Membrane antigen MN; P54/58N; Renal cell carcinoma-associated antigen G250; RCC-associated antigen G250; pMW1
- Molecular Weight(Da):
- 49kD
- Function:
- catalytic activity:H(2)CO(3) = CO(2) + H(2)O.,cofactor:Zinc.,function:Reversible hydration of carbon dioxide. Participates in pH regulation. May be involved in the control of cell proliferation and transformation. Appears to be a novel specific biomarker for a cervical neoplasia.,induction:By hypoxia.,PTM:Asn-346 bears high-mannose type glycan structures.,similarity:Belongs to the alpha-carbonic anhydrase family.,subcellular location:Found on the surface microvilli and in the nucleus, particularly in nucleolus.,subunit:Forms oligomers linked by disulfide bonds.,tissue specificity:Expressed primarily in carcinoma cells lines. Expression is restricted to very few normal tissues and the most abundant expression is found in the epithelial cells of gastric mucosa.,
- Subcellular Location:
- Membranous
- Expression:
- Expressed primarily in carcinoma cells lines. Expression is restricted to very few normal tissues and the most abundant expression is found in the epithelial cells of gastric mucosa.
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- Antibody-FAQs
- Products Images
- Human stomach tissue was stained with Anti-CA IX (PTR2373) Antibody
- Human colon carcinoma tissue was stained with Anti-CA IX (PTR2373) Antibody
- Human colon carcinoma tissue was stained with Anti-CA IX (PTR2373) Antibody
- Human renal clear cell carcinoma tissue was stained with Anti-CA IX (PTR2373) Antibody
- Human renal clear cell carcinoma tissue was stained with Anti-CA IX (PTR2373) Antibody