• Target：
• MEK-4

• Gene Name：
• PAX5

• Protein Name：
• PAX-5

• Human Gene Id：
• 5079

• Human Swiss Prot No：
• Q02548

• Mouse Gene Id：
• 18507

• Mouse Swiss Prot No：
• Q02650

• Immunogen：
• Synthesized peptide derived from human PAX-5 AA range:300-383

• Specificity：
• This antibody detects endogenous levels of PAX-5 protein.

• Formulation：
• PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

• Source：
• Mouse, Monoclonal/IgG

• Dilution：
• IHC 1:200-400. ELISA 1:500-5000

• Purification：
• The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• Paired box protein Pax-5 (B-cell-specific transcription factor) (BSAP)

• Molecular Weight(Da)：
• 42kD

• Observed Band(KD)：
• 42kD

• Function：
• developmental stage:Expressed at early B-cell differentiation, in the developing CNS and in adult testis.,disease:A chromosomal aberration involving PAX5 is a cause of acute lymphoblastic leukemia. Translocation t(9;18)(p13;q11.2) with ZNF521. Translocation t(9;3)(p13;p14.1) with FOXP1. Translocation t(9;12)(p13;p13) with ETV6.,function:May play an important role in B-cell differentiation as well as neural development and spermatogenesis. Involved in the regulation of the CD19 gene, a B-lymphoid-specific target gene.,PTM:O-glycosylated.,similarity:Contains 1 paired domain.,subunit:Interacts with DAXX (By similarity). Binds DNA as a monomer. Binds TLE4.,

• Subcellular Location：
• Nuclear

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