IL28B Polyclonal Antibody

    • Catalog No.:YN0229
    • Applications:WB;ELISA
    • Reactivity:Human;Mouse
      • Target:
      • IL28B
      • Fields:
      • >>Cytokine-cytokine receptor interaction;>>JAK-STAT signaling pathway
      • Gene Name:
      • IL28B IFNL3 IFNL4 IL28C ZCYTO22
      • Protein Name:
      • Interleukin-28B (IL-28B) (Cytokine Zcyto22) (Interferon lambda-3) (IFN-lambda-3) (Interferon lambda-4) (IFN-lambda-4) (Interleukin-28C) (IL-28C)
      • Human Swiss Prot No:
      • Q8IZI9
      • Mouse Swiss Prot No:
      • Q8CGK6
      • Immunogen:
      • Synthesized peptide derived from human protein . at AA range: 100-180
      • Specificity:
      • IL28B Polyclonal Antibody detects endogenous levels of protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500-2000 ELISA 1:5000-20000
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Observed Band(KD):
      • 21kD
      • Background:
      • This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq, Jul 2008],
      • Function:
      • caution:It is uncertain whether Met-1 or Met-5 is the initiator.,function:Cytokine with immunomodulatory activity. Up-regulates MHC class I antigen expression. Displays potent antiviral activity. Also displays antitumor activity. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.,induction:By viral infections or double stranded RNA.,similarity:Belongs to the IL-28/IL-29 family.,
      • Subcellular Location:
      • Secreted .
      • Expression:
      • Pooled,
      • Products Images
      • Western blot analysis of lysates from Jurkat cells, primary antibody was diluted at 1:1000, 4°over night