RASA2 Polyclonal Antibody

  • Catalog No.：YN1855
  • Applications：WB;ELISA
  • Reactivity：Human;Mouse;Rat
    • Target：
    • RASA2
    • Fields：
    • >>MAPK signaling pathway;>>Ras signaling pathway;>>Viral carcinogenesis
    • Gene Name：
    • RASA2 GAP1M RASGAP
    • Protein Name：
    • Ras GTPase-activating protein 2 (GAP1m)
    • Human Gene Id：
    • 5922
    • Human Swiss Prot No：
    • Q15283
    • Mouse Swiss Prot No：
    • P58069
    • Immunogen：
    • Synthesized peptide derived from part region of human protein
    • Specificity：
    • RASA2 Polyclonal Antibody detects endogenous levels of protein.
    • Formulation：
    • Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
    • Source：
    • Polyclonal, Rabbit,IgG
    • Dilution：
    • WB 1:500-2000 ELISA 1:5000-20000
    • Purification：
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • Concentration：
    • 1 mg/ml
    • Storage Stability：
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • Observed Band(KD)：
    • 93kD
    • Background：
    • The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014],
    • Function：
    • function:Inhibitory regulator of the Ras-cyclic AMP pathway. Binds inositol tetrakisphosphate (IP4).,similarity:Contains 1 Btk-type zinc finger.,similarity:Contains 1 PH domain.,similarity:Contains 1 Ras-GAP domain.,similarity:Contains 2 C2 domains.,
    • Subcellular Location：
    • Cytoplasm. Cytoplasm, perinuclear region.
    • Expression：
    • Blood,Brain,

    Attributes

    • Code：
    • YN1855
    • Size
    • 40μL / 100μL / 200μL
    • Price$：
    • 150 / 280 / 450
    • Delivery：
    • 2024-09-02
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