LDHD Polyclonal Antibody

  • Catalog No.:YN5523
  • Applications:WB
  • Reactivity:Human;Mouse;Rat
    • Target:
    • LDHD
    • Fields:
    • >>Pyruvate metabolism;>>Metabolic pathways
    • Gene Name:
    • LDHD
    • Protein Name:
    • Probable D-lactate dehydrogenase, mitochondrial
    • Human Swiss Prot No:
    • Q86WU2
    • Mouse Swiss Prot No:
    • Q7TNG8
    • Immunogen:
    • Recombinant Protein of LDHD
    • Specificity:
    • The antibody detects endogenous LDHD protein.
    • Formulation:
    • PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
    • Source:
    • Polyclonal, Rabbit,IgG
    • Dilution:
    • WB 1:1000-5000
    • Purification:
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • Storage Stability:
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • Other Name:
    • Probable D-lactate dehydrogenase, mitochondrial (DLD) (Lactate dehydrogenase D) (EC 1.1.2.4)
    • Observed Band(KD):
    • 55kD
    • Background:
    • The protein encoded by this gene belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. The similar protein in yeast has both D-lactate and D-glycerate dehydrogenase activities. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008],
    • Function:
    • catalytic activity:(R)-lactate + 2 ferricytochrome c = pyruvate + 2 ferrocytochrome c.,cofactor:FAD.,similarity:Belongs to the FAD-binding oxidoreductase/transferase type 4 family.,similarity:Contains 1 FAD-binding PCMH-type domain.,subunit:Interacts with CSRP3.,tissue specificity:Expressed moderately in heart and liver and at lower levels in skeletal muscle and kidney.,
    • Subcellular Location:
    • Mitochondrion .
    • Expression:
    • Expressed moderately in heart and liver and at lower levels in skeletal muscle and kidney.