LDHD Polyclonal Antibody
- Catalog No.:YN5523
- Applications:WB
- Reactivity:Human;Mouse;Rat
- Target:
- LDHD
- Fields:
- >>Pyruvate metabolism;>>Metabolic pathways
- Gene Name:
- LDHD
- Protein Name:
- Probable D-lactate dehydrogenase, mitochondrial
- Human Gene Id:
- 197257
- Human Swiss Prot No:
- Q86WU2
- Mouse Gene Id:
- 52815
- Mouse Swiss Prot No:
- Q7TNG8
- Immunogen:
- Recombinant Protein of LDHD
- Specificity:
- The antibody detects endogenous LDHD protein.
- Formulation:
- PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:1000-5000
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- Probable D-lactate dehydrogenase, mitochondrial (DLD) (Lactate dehydrogenase D) (EC 1.1.2.4)
- Observed Band(KD):
- 55kD
- Background:
- The protein encoded by this gene belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. The similar protein in yeast has both D-lactate and D-glycerate dehydrogenase activities. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008],
- Function:
- catalytic activity:(R)-lactate + 2 ferricytochrome c = pyruvate + 2 ferrocytochrome c.,cofactor:FAD.,similarity:Belongs to the FAD-binding oxidoreductase/transferase type 4 family.,similarity:Contains 1 FAD-binding PCMH-type domain.,subunit:Interacts with CSRP3.,tissue specificity:Expressed moderately in heart and liver and at lower levels in skeletal muscle and kidney.,
- Subcellular Location:
- Mitochondrion .
- Expression:
- Expressed moderately in heart and liver and at lower levels in skeletal muscle and kidney.
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