CACNG2 Polyclonal Antibody

    • Catalog No.:YN5652
    • Applications:WB;IHC;IF
    • Reactivity:Human;Mouse;Rat
      • Target:
      • CACNG2
      • Fields:
      • >>MAPK signaling pathway;>>Cardiac muscle contraction;>>Adrenergic signaling in cardiomyocytes;>>Oxytocin signaling pathway;>>Hypertrophic cardiomyopathy;>>Arrhythmogenic right ventricular cardiomyopathy;>>Dilated cardiomyopathy
      • Gene Name:
      • CACNG2
      • Protein Name:
      • Voltage-dependent calcium channel gamma-2 subunit
      • Human Swiss Prot No:
      • Q9Y698
      • Mouse Swiss Prot No:
      • O88602
      • Immunogen:
      • Synthetic Peptide of CACNG2 AA range: 58-108
      • Specificity:
      • The antibody detects endogenous CACNG2 protein.
      • Formulation:
      • PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:1000-2000 IHC 1:200-500. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • Voltage-dependent calcium channel gamma-2 subunit;Neuronal voltage-gated calcium channel gamma-2 subunit;Transmembrane AMPAR regulatory protein gamma-2;TARP gamma-2
      • Observed Band(KD):
      • 36kD
      • Background:
      • calcium voltage-gated channel auxiliary subunit gamma 2(CACNG2) Homo sapiens The protein encoded by this gene is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family. This gene is a susceptibility locus for schizophrenia. [provided by RefSeq, Dec 2010],
      • Function:
      • function:Thought to stabilize the calcium channel in an inactivated (closed) state.,PTM:Phosphorylation of Thr-321 impairs interaction with DLG1 and DLG4.,similarity:Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.,subunit:The L-type calcium channel is composed of five subunits: alpha-1, alpha-2/delta, beta and gamma. Interacts with the PDZ domains of DLG4/PSD-95 and DLG1/SAP97. May interact with GOPC.,tissue specificity:Brain.,
      • Subcellular Location:
      • Membrane; Multi-pass membrane protein. Cell junction, synapse, synaptosome .
      • Expression:
      • Brain.
      • Products Images
      • Western blot analysis of 1) Human Brain Tissue, 2) Mouse Brain Tissue, 3) Rat Brain Tissue using CACNG2 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
      • Immunohistochemical analysis of paraffin-embedded Rat Brain Tissue using CACNG2 Polyclonal Antibody.