eIF4B (Phospho Ser406) rabbit pAb

  • Catalog No.:YP1327
  • Applications:WB
  • Reactivity:Human;Mouse;Rat
    • Target:
    • eIF4B
    • Fields:
    • >>mTOR signaling pathway;>>PI3K-Akt signaling pathway;>>Proteoglycans in cancer
    • Gene Name:
    • EIF4B
    • Protein Name:
    • eIF4B (Ser406)
    • Human Gene Id:
    • 1975
    • Human Swiss Prot No:
    • P23588
    • Mouse Swiss Prot No:
    • Q8BGD9
    • Immunogen:
    • Synthesized phosho peptide around human eIF4B (Ser406)
    • Specificity:
    • This antibody detects endogenous levels of Human Mouse Rat eIF4B (phospho-Ser406)
    • Formulation:
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • Source:
    • Polyclonal, Rabbit,IgG
    • Dilution:
    • WB 1:1000-2000
    • Purification:
    • The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
    • Concentration:
    • 1 mg/ml
    • Storage Stability:
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • Other Name:
    • Eukaryotic translation initiation factor 4B (eIF-4B)
    • Observed Band(KD):
    • 80kD
    • Function:
    • function:Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subunit:Self-associates and interacts with EIF3 p170 subunit.,
    • Subcellular Location:
    • cytosol,polysome,eukaryotic translation initiation factor 4F complex,dendrite,neuronal cell body,
    • Expression:
    • Adipose tissue,Brain,Cervix carcinoma,Epithelium,Liver,Lung