eIF4B (Phospho Ser406) rabbit pAb
- Catalog No.:YP1327
- Applications:WB
- Reactivity:Human;Mouse;Rat
- Target:
- eIF4B
- Fields:
- >>mTOR signaling pathway;>>PI3K-Akt signaling pathway;>>Proteoglycans in cancer
- Gene Name:
- EIF4B
- Protein Name:
- eIF4B (Ser406)
- Human Gene Id:
- 1975
- Human Swiss Prot No:
- P23588
- Mouse Gene Id:
- 75705
- Mouse Swiss Prot No:
- Q8BGD9
- Immunogen:
- Synthesized phosho peptide around human eIF4B (Ser406)
- Specificity:
- This antibody detects endogenous levels of Human Mouse Rat eIF4B (phospho-Ser406)
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:1000-2000
- Purification:
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- Eukaryotic translation initiation factor 4B (eIF-4B)
- Observed Band(KD):
- 80kD
- Function:
- function:Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subunit:Self-associates and interacts with EIF3 p170 subunit.,
- Subcellular Location:
- cytosol,polysome,eukaryotic translation initiation factor 4F complex,dendrite,neuronal cell body,
- Expression:
- Adipose tissue,Brain,Cervix carcinoma,Epithelium,Liver,Lung
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