EPHB3 (Phospho Tyr608) rabbit pAb

  • Catalog No.:YP1610
  • Applications:WB;ELISA
  • Reactivity:Human;Mouse;Rat
    • Target:
    • EPHB3
    • Fields:
    • >>Axon guidance
    • Gene Name:
    • EPHB3 ETK2 HEK2 TYRO6
    • Protein Name:
    • EPHB3 (Phospho Tyr608)
    • Human Gene Id:
    • 2049
    • Human Swiss Prot No:
    • P54753
    • Mouse Swiss Prot No:
    • P54754
    • Immunogen:
    • Synthesized peptide derived from human EPHB3 (Phospho Tyr608)
    • Specificity:
    • This antibody detects endogenous levels of Human,Mouse,Rat EPHB3 (Phospho Tyr608)
    • Formulation:
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • Source:
    • Polyclonal, Rabbit,IgG
    • Dilution:
    • WB 1:1000-2000 ELISA 1:5000-20000
    • Purification:
    • The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
    • Concentration:
    • 1 mg/ml
    • Storage Stability:
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • Other Name:
    • Ephrin type-B receptor 3 (EC 2.7.10.1;EPH-like tyrosine kinase 2;EPH-like kinase 2;Embryonic kinase 2;EK2;hEK2;Tyrosine-protein kinase TYRO6)
    • Observed Band(KD):
    • 73kD
    • Background:
    • Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into two groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. This gene encodes a receptor for ephrin-B family members. [provided by RefSeq, Mar 2010],
    • Function:
    • catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:Receptor for members of the ephrin-B family. Binds to ephrin-B1 and -B2.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SAM (sterile alpha motif) domain.,similarity:Contains 2 fibronectin type-III domains.,tissue specificity:Ubiquitous.,
    • Subcellular Location:
    • Cell membrane ; Single-pass type I membrane protein . Cell projection, dendrite .
    • Expression:
    • Ubiquitous.