RSK3 (Phospho Thr353) rabbit pAb

  • Catalog No.：YP1635
  • Applications：WB;ELISA
  • Reactivity：Human;Mouse
    • Target：
    • RSK3
    • Fields：
    • >>MAPK signaling pathway;>>Oocyte meiosis;>>mTOR signaling pathway;>>Thermogenesis;>>Long-term potentiation;>>Neurotrophin signaling pathway;>>Progesterone-mediated oocyte maturation;>>Insulin resistance;>>Yersinia infection;>>Chemical carcinogenesis - receptor activation
    • Gene Name：
    • RPS6KA2 MAPKAPK1C RSK3
    • Protein Name：
    • RSK3 (Phospho Thr353)
    • Human Gene Id：
    • 6196
    • Human Swiss Prot No：
    • Q15349
    • Mouse Swiss Prot No：
    • Q9WUT3
    • Immunogen：
    • Synthesized peptide derived from human RSK3 (Phospho Thr353)
    • Specificity：
    • This antibody detects endogenous levels of Human,Mouse RSK3 (Phospho Thr353)
    • Formulation：
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • Source：
    • Polyclonal, Rabbit,IgG
    • Dilution：
    • WB 1:1000-2000 ELISA 1:5000-20000
    • Purification：
    • The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
    • Concentration：
    • 1 mg/ml
    • Storage Stability：
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • Other Name：
    • Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2;EC 2.7.11.1;90 kDa ribosomal protein S6 kinase 2;p90-RSK 2;p90RSK2;MAP kinase-activated protein kinase 1c;MAPK-activated protein kinase 1c;MAPKAP kinase 1c;MAPKAPK-1c;Ribosomal S6 kinase 3;RSK-3;pp90RSK3)
    • Observed Band(KD)：
    • 80kD
    • Background：
    • catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by multiple phosphorylations on threonine and serine residues.,function:Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.,PTM:Autophosphorylated on Ser-377, as part of the activation process.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 2 protein kinase domains.,subunit:Forms a complex with either ERK1 or ERK2 in quiescent cells. Transiently dissociates following mitogenic stimulation.,tissue specificity:Expressed in many tissues. Highest expression in lung and skeletal muscle.,
    • Function：
    • protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, intracellular signaling cascade, protein kinase cascade, phosphorylation,
    • Subcellular Location：
    • Nucleus . Cytoplasm .
    • Expression：
    • Widely expressed with higher expression in lung, skeletal muscle, brain, uterus, ovary, thyroid and prostate.

    Attributes

    • Code：
    • YP1635
    • Size
    • 50μL / 100μL / 200μL
    • Price$：
    • 190 / 340 / 600
    • Delivery：
    • 2024-12-27
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