Actin β Polyclonal Antibody

  • Catalog No.：YT0099
  • Applications：IF;WB;IHC;ELISA
  • Reactivity：Human;Mouse;Rat;Chicken;Globefish;Bovine;Hamster;Pig;Ovine;Cat;Pig;Dog;Sheep
    • Target：
    • Actin β
    • Fields：
    • >>Rap1 signaling pathway;>>Phagosome;>>Apoptosis;>>Hippo signaling pathway;>>Focal adhesion;>>Adherens junction;>>Tight junction;>>Platelet activation;>>Neutrophil extracellular trap formation;>>Leukocyte transendothelial migration;>>Thermogenesis;>>Regulation of actin cytoskeleton;>>Thyroid hormone signaling pathway;>>Oxytocin signaling pathway;>>Gastric acid secretion;>>Amyotrophic lateral sclerosis;>>Bacterial invasion of epithelial cells;>>Vibrio cholerae infection;>>Pathogenic Escherichia coli infection;>>Shigellosis;>>Salmonella infection;>>Yersinia infection;>>Influenza A;>>Proteoglycans in cancer;>>Hepatocellular carcinoma;>>Hypertrophic cardiomyopathy;>>Arrhythmogenic right ventricular cardiomyopathy;>>Dilated cardiomyopathy;>>Viral myocarditis;>>Fluid shear stress and atherosclerosis
    • Gene Name：
    • ACTB
    • Protein Name：
    • Actin cytoplasmic 1
    • Human Gene Id：
    • 60
    • Human Swiss Prot No：
    • P60709
    • Mouse Swiss Prot No：
    • P60710
    • Immunogen：
    • Synthesized peptide derived from the N-terminal region of human Actin β. AA range: 1-80
    • Specificity：
    • Actin β Polyclonal Antibody detects endogenous levels of Actin β protein.
    • Formulation：
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • Source：
    • Polyclonal, Rabbit,IgG
    • Dilution：
    • IF 1:50-200 WB 1:2000 - 1:10000. IHC 1:100 - 1:300. ELISA: 1:20000. Not yet tested in other applications.
    • Purification：
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • Concentration：
    • 1 mg/ml
    • Storage Stability：
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • Other Name：
    • ACTB;Actin; cytoplasmic 1;Beta-actin;Actin β;β-Actin;Beta actin
    • Observed Band(KD)：
    • 42kD
    • Background：
    • This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, and integrity. This actin is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins. [provided by RefSeq, Jul 2008],
    • Function：
    • disease:Defects in ACTB are a cause of dystonia juvenile-onset (DYTJ) [MIM:607371]. DYTJ is a form of dystonia with juvenile onset. Dystonia is defined by the presence of sustained involuntary muscle contraction, often leading to abnormal postures. DYTJ patients manifest progressive, generalized, dopa-unresponsive dystonia, developmental malformations and sensory hearing loss.,function:Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.,miscellaneous:In vertebrates 3 main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cytoskeleton and as mediators of internal cell motility.,similarity:Belongs to the
    • Subcellular Location：
    • Cytoplasm, cytoskeleton . Nucleus . Localized in cytoplasmic mRNP granules containing untranslated mRNAs. .
    • Expression：
    • B-cell lymphoma,Brain,Cajal-Retzius cell,Eye,Fetal brain cortex,Foreskin,Hepatocellular car

    Attributes

    • Code：
    • YT0099
    • Size
    • 100μL / 500μL / 1mL
    • Price$：
    • 184 / 800 / 1360
    • Delivery：
    • 2024-11-23
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