ARHGAP12 Polyclonal Antibody
- Catalog No.:YT0315
- Applications:WB;ELISA
- Reactivity:Human;Mouse;Rat
- Target:
- ARHGAP12
- Gene Name:
- ARHGAP12
- Protein Name:
- Rho GTPase-activating protein 12
- Human Gene Id:
- 94134
- Human Swiss Prot No:
- Q8IWW6
- Mouse Gene Id:
- 75415
- Mouse Swiss Prot No:
- Q8C0D4
- Immunogen:
- Synthesized peptide derived from ARHGAP12 . at AA range: 310-390
- Specificity:
- ARHGAP12 Polyclonal Antibody detects endogenous levels of ARHGAP12 protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- ARHGAP12;Rho GTPase-activating protein 12;Rho-type GTPase-activating protein 12
- Observed Band(KD):
- 100kD
- Background:
- This gene encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein may be involved in suppressing tumor formation by regulating cell invasion and adhesion. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012],
- Function:
- function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.,similarity:Contains 1 PH domain.,similarity:Contains 1 Rho-GAP domain.,similarity:Contains 1 SH3 domain.,similarity:Contains 2 WW domains.,
- Subcellular Location:
- cytosol,
- Expression:
- PCR rescued clones,Placenta,T-cell,Testis,Uterus,
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