Cadherin-22 Polyclonal Antibody

    • Catalog No.:YT0598
    • Applications:WB;IHC;IF;ELISA
    • Reactivity:Human;Mouse;Rat
      • Target:
      • Cadherin-22
      • Gene Name:
      • CDH22
      • Protein Name:
      • Cadherin-22
      • Human Swiss Prot No:
      • Q9UJ99
      • Mouse Swiss Prot No:
      • Q9WTP5
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human CDH22. AA range:111-160
      • Specificity:
      • Cadherin-22 Polyclonal Antibody detects endogenous levels of Cadherin-22 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • CDH22;C20orf25;Cadherin-22;Pituitary and brain cadherin;PB-cadherin
      • Observed Band(KD):
      • 84kD
      • Background:
      • This gene is a member of the cadherin superfamily. The gene product is composed of five cadherin repeat domains and a cytoplasmic tail similar to the highly conserved cytoplasmic region of classical cadherins. Expressed predominantly in the brain, this putative calcium-dependent cell adhesion protein may play an important role in morphogenesis and tissue formation in neural and non-neural cells during development and maintenance of the brain and neuroendocrine organs. [provided by RefSeq, Jul 2008],
      • Function:
      • function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. PB-cadherins may have a role in the morphological organization of pituitary gland and brain tissues.,similarity:Contains 5 cadherin domains.,
      • Subcellular Location:
      • Cell membrane ; Single-pass type I membrane protein .
      • Expression:
      • Brain,Testis,
      • Products Images
      • Immunofluorescence analysis of NIH/3T3 cells, using CDH22 Antibody. The picture on the right is blocked with the synthesized peptide.
      • Immunohistochemistry analysis of paraffin-embedded human brain tissue, using CDH22 Antibody. The picture on the right is blocked with the synthesized peptide.
      • Western blot analysis of lysates from rat brain cells, using CDH22 Antibody. The lane on the right is blocked with the synthesized peptide.