CD70 Polyclonal Antibody
- Catalog No.:YT0774
- Applications:WB;ELISA
- Reactivity:Human;Mouse
- Target:
- CD70
- Fields:
- >>Cytokine-cytokine receptor interaction
- Gene Name:
- CD70
- Protein Name:
- CD70 antigen
- Human Gene Id:
- 970
- Human Swiss Prot No:
- P32970
- Mouse Swiss Prot No:
- O55237
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human CD70. AA range:68-117
- Specificity:
- CD70 Polyclonal Antibody detects endogenous levels of CD70 protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- CD70;CD27L;CD27LG;TNFSF7;CD70 antigen;CD27 ligand;CD27-L;Tumor necrosis factor ligand superfamily member 7;CD antigen CD70
- Observed Band(KD):
- 30kD
- Background:
- The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. [provided by RefSeq, Jul 2008],
- Function:
- function:Cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.,similarity:Belongs to the tumor necrosis factor family.,subunit:Homotrimer.,
- Subcellular Location:
- Membrane ; Single-pass type II membrane protein .
- Expression:
- B-cell,Kidney,
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- Antibody-FAQs
- Products Images
- Western Blot analysis of various cells using CD70 Polyclonal Antibody diluted at 1:2000
- Western blot analysis of the lysates from Jurkat cells using CD70 antibody.