CMTM4 Polyclonal Antibody
- Catalog No.:YT0986
- Applications:WB;IHC;IF;ELISA
- Reactivity:Human;Mouse
- Target:
- CMTM4
- Gene Name:
- CMTM4
- Protein Name:
- CKLF-like MARVEL transmembrane domain-containing protein 4
- Human Gene Id:
- 146223
- Human Swiss Prot No:
- Q8IZR5
- Mouse Gene Id:
- 97487
- Mouse Swiss Prot No:
- Q8CJ61
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human CKLF4. AA range:161-210
- Specificity:
- CMTM4 Polyclonal Antibody detects endogenous levels of CMTM4 protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000. IF 1:100-300 Not yet tested in other applications.
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- CMTM4;CKLFSF4;CKLF-like MARVEL transmembrane domain-containing protein 4;Chemokine-like factor superfamily member 4
- Observed Band(KD):
- 26kD
- Background:
- This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies of signaling molecules. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 16. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
- Function:
- similarity:Belongs to the chemokine-like factor family.,similarity:Contains 1 MARVEL domain.,tissue specificity:Highly expressed in testis and prostate.,
- Subcellular Location:
- Membrane ; Multi-pass membrane protein .
- Expression:
- Highly expressed in testis and prostate.
CMTM4 regulates epithelial–mesenchymal transition and PD-L1 expression in head and neck squamous cell carcinoma. MOLECULAR CARCINOGENESIS Mol Carcinogen. 2021 Aug;60(8):556-566 IHC Human mucosa,dysplasia tissue,HNSCC tissue
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- Antibody-FAQs
- Products Images
- Immunofluorescence analysis of A549. 1,primary Antibody(red) was diluted at 1:200(4°C overnight). 2, Goat Anti Rabbit IgG (H&L) - Alexa Fluor 594 Secondary antibody was diluted at 1:1000(room temperature, 50min).3, Picture B: DAPI(blue) 10min.
- Western Blot analysis of HELA cells using CMTM4 Polyclonal Antibody
- Western blot analysis of CKLF4 Antibody. The lane on the right is blocked with the CKLF4 peptide.
- Immunohistochemistryt analysis of paraffin-embedded human breast carcinoma, using CKLF4 Antibody. The lane on the right is blocked with the CKLF4 peptide.